Cyclin-Dependent Kinase Inhibitor p21

A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3.

Also Known As:

CDK2-Associated Protein 20 kDa; CDKN1 Protein; CDKN1A Protein; Cdk-Interacting Protein 1; Cdk2 Inhibitor Protein; Cell Cycle Regulator p21; Cyclin Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor 1A Protein; Senescent Cell-Derived Inhibitor Protein 1; p21 Cell Cycle Regulator; p21 Cyclin Kinase Inhibitor; CDK2 Associated Protein 20 kDa; Cdk Interacting Protein 1; Cyclin Dependent Kinase Inhibitor 1A Protein; Cyclin Dependent Kinase Inhibitor p21; Senescent Cell Derived Inhibitor Protein 1

Pharmalogical Action Categories:

Protein Kinase Inhibitors

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Poly-ADP-Ribose Binding Proteins
      - Cyclin-Dependent Kinase Inhibitor p21: 245
  - Nuclear Proteins: 2678
    - Poly-ADP-Ribose Binding Proteins
      - Cyclin-Dependent Kinase Inhibitor p21: 245
  - Cell Cycle Proteins: 807
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17
      - Cyclin-Dependent Kinase Inhibitor p21: 245
  - Intracellular Signaling Peptides and Proteins: 32
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17
      - Cyclin-Dependent Kinase Inhibitor p21: 245
  - Neoplasm Proteins: 2
    - Tumor Suppressor Proteins: 1683
      - Cyclin-Dependent Kinase Inhibitor Proteins: 17
        Cyclin-Dependent Kinase Inhibitor p21: 245
- Peptides: 82426
  - Intracellular Signaling Peptides and Proteins: 32
    - Cyclin-Dependent Kinase Inhibitor Proteins: 17
      - Cyclin-Dependent Kinase Inhibitor p21: 245

Dong-Zhu Ma Selected Research

Dong-Zhu Ma Research Topics

Disease

Drug/Important Bio-Agent (IBA)